溃结安康汤对溃疡性结肠炎大鼠MDA影响的研究  

Research about the influence of Kuijieankang decoction to rats MDA with ulcerative colitis

作　　者：陶弘武[1] 柳越冬[1] 李开明[1] 

机构地区：[1]辽宁中医药大学 辽宁中医药大学附属第三医院

出　　处：《实用中医内科杂志》2009年第4期-,共2页Journal of Practical Traditional Chinese Internal Medicine

基　　金：辽宁省自然基金项目(20072072)

摘　　要：[目的]研究溃结安康汤对溃疡性结肠炎大鼠MDA影响及其作用机制。[方法]健康Wistar大鼠,随机分为空白对照组、模型组、补脾益肠丸组、SASP组、溃结安康汤组。TNBS/乙醇法建立溃疡性结肠炎大鼠模型。分组灌胃治疗后,检测溃结大鼠结肠组织MDA含量。[结果]模型组与正常组比较,MDA含量升高,具有统计学意义(P<0.05);补脾益肠丸组、SASP组、溃结安康汤组与模型组比较,MDA含量下降,具有统计学意义(P<0.05);溃结安康汤组与补脾益肠丸组、SASP组比较,MDA含量明显下降,具有统计学意义(P<0.05)。[结论]溃结安康汤可以降低溃疡性结肠炎大鼠模型中结肠组织MDA含量。[Objective]To research into the influence of Kuijieankang decoction to rats MDA with ulcerative colitis and its mechanism of action.[Method]Some healthy Wistar rats were randomLy divided into control group,model group,Bupiyichang pill group,SASP group,and Kuijieankang decoction group.The rat model of ulcerative colitis was established by TNBS/ethanol method.Detecting MDA content of rats colon tissue with ulcerative colitis after intragastric administration.[Results]Comparing with normal group,the MDA conten...

关 键 词：溃疡性结肠炎 丙二醛(MDA) 溃结安康汤 

分 类 号：R285.5[医药卫生—中药学]