Differential Gene Expression Profiles in Coronary Heart Disease Patients of Blood Stasis Syndrome in Traditional Chinese Medicine and Clinical Role of Target Gene  

作　　者：马晓娟 殷惠军 陈可冀 

机构地区：[1]Department of Cardiovascular Disease,Xiyuan Hospital,China Academy of Traditional Chinese Medicine

出　　处：《Chinese Journal of Integrative Medicine》2009年第2期101-106,共6页中国结合医学杂志（英文版）

基　　金：Supported by the Major Research Plan of National Natural Science Foundation of China(No.90409021)

摘　　要：Objective:To investigate the differential gene expression profiles in coronary heart disease(CHD) patients of blood-stasis syndrome(BSS) by oligonucleotide microarray technique,and the clinical significance of target gene.Methods:Subjects were assigned to CHD patients with BSS(n=8),CHD patients without BSS (n=8),and BSS patients without CHD(n=8) based on coronary angiography and the diagnostic criteria of BSS. The sex- and age-matched healthy volunteers(n=8) were enrolled as the control group.Venous blood s...Objective:To investigate the differential gene expression profiles in coronary heart disease(CHD) patients of blood-stasis syndrome(BSS) by oligonucleotide microarray technique,and the clinical significance of target gene.Methods:Subjects were assigned to CHD patients with BSS(n=8),CHD patients without BSS (n=8),and BSS patients without CHD(n=8) based on coronary angiography and the diagnostic criteria of BSS. The sex- and age-matched healthy volunteers(n=8) were enrolled as the control group.Venous blood s...

关 键 词：coronary heart disease blood-stasis syndrome differential gene expression profile target gene 

分 类 号：R259[医药卫生—中西医结合]