白背三七总黄酮的提取工艺研究  

Extraction of Total Flavonoids in Gynura divaricata(L.) DC.

作　　者：王津江[1,2] 陈磊[1] 宋洪涛[1] 张国刚[2] 李厚全[1,2] 

机构地区：[1]南京军区福州总医院药学科,福州350025 [2]沈阳药科大学中药学院

出　　处：《中国药师》2009年第2期146-149,共4页China Pharmacist

基　　金：福建省中医药科研项目(wzy0606);福建省科技计划项目(2008Y0086)

摘　　要：目的:考察白背三七总黄酮的提取工艺。方法:以总黄酮得率为主要考察指标,出膏率为参考指标,采用单因素试验法考察浸泡时间、药材部位、药材粒径等10个影响因素,用正交试验法考察乙醇浓度、提取温度、料液比等3个影响因素。结果:单因素试验得出的优化工艺条件:提取方法为超声法,浸泡时间50 min,药材部位为茎与叶,乙醇浓度60%,药材粒径≤12目,提取温度60℃,料液比1:40,超声时间15 min,超声功率500 W,提取次数2次。正交试验得出的最佳提取工艺:用40倍量60%的乙醇,在60℃下超声提取2次。结论:该提取工艺可为中药白背三七的开发利用提供参考。Objective:To investigate the extraction process of total flavonoids in Gynura divaricata(L.) DC.Method:The yielding rate of total flavonoids was used as main indicator,and the extraction ratio as reference indicator,ten factors,such as soaking time, organs of the plant,the diameter of drug powder were investigated by single factor method,and three factors include alcohol concentration, extraction temperature and the ratio of solid to liquid were investigated by orthogonal method.Result:The optimal extractin...

关 键 词：白背三七 总黄酮 提取工艺 超声提取 

分 类 号：R284.2[医药卫生—中药学]