ESRD患者颈动脉内中膜增厚及其可能影响因素分析  

The Increasing Carotid Intima-media Thickness and the Possible Risk Factors in Patients with End-stage Renal Disease

作　　者：张坤英[1] 刘惠兰[1] 段晓峰[1] 李国刚[1] 徐丰博[1] 

机构地区：[1]首都医科大学附属复兴医院肾内科

出　　处：《首都医科大学学报》2009年第2期126-129,共4页Journal of Capital Medical University

基　　金：北京西城区科技计划(2008018)资助项目~~

摘　　要：目的比较终末期肾脏病(end-stage renal disease,ESRD)患者维持性血液透析者(maintenance hemodialysis,MHD)和非血液透析者颈动脉内中膜增厚程度的不同,探讨影响终末期肾脏病患者动脉粥样硬化(atherosclerosis,AS)发生发展的可能因素。方法选择病情稳定的MHD患者45例;慢性肾脏病4~5期未透析(chronic kidney disease not subjected to hemodialysis,CKD-non-HD)患者23例;健康对照组20例。采用高分辨率超声测定颈总动脉(common carotid arteries,CCA)、颈动脉分叉处(thebifurcation of carotid arteries,CB)及颈内动脉起始段(internal carotid arteries,CI)内中膜厚度(intima-media thickness,IMT)。结果MHD和CKD-non-HD患者CCA-IMT、CB-IMT及CI-IMT均较对照组高(P均<0.05)。但MHD组和CKD-non-HD组之间CCA-IMT、CB-IMT及CI-...Objective The aim of our study is to find out whether atherosclerosis of dialysis patients is effectively accelerated due to the fact that many such patients at the start of dialysis treatment.Methods Using B-mode ultrasonography,we conducted a cross-sectional study to compare intima-media thickness in the common carotid arteries(CC),in the area of bifurcation(CB)and in the proximal part of internal carotid arteries(CI)for 45 MHD patients,of which 23 patients had chronic kidney diseases not subjected to hem...

关 键 词：终末期肾脏病 动脉粥样硬化 内中膜厚度 

分 类 号：R459.5[医药卫生—治疗学]