治疗药物监测进展  

Development of therapeutic drug monitoring

作　　者：马骏[1] 谢景文[1] 孙卫胜[1] 谢华[1] 贾正平[1] 刘静[1] 

机构地区：[1]兰州军区总医院药材科,兰州730050

出　　处：《药学实践杂志》2000年第4期250-254,244,共6页Journal of Pharmaceutical Practice

基　　金：全军"九五"医学科研规划第二批科研基金面上项目!编号 98M0 18

摘　　要：目的 :阐述治疗药物监测的必要性和测定技术。方法 :对所监测的药物、取样和分析方法进行综述。结果 :说明了药物监测的范围和指标 ,样品需求的条件 ,重点比较了色谱技术和免疫分析法在TDM中的应用和各自的优越性。结论 :确保TDM的顺利进行 ,必须具备临床知识和掌握分析技术。OBJECTIVE:To review the principles of therapeutic drug monitoring (TDM)and the role of analytical techniques in TDM.METHODS:The content included ranges of monitored drugs,sampling requirements and analytical aspects.RESULTS:This article explained the criteria for undertaking drug level monitoring and the requirements of sampling,compared techniques of chromatographic and immunoassay.CONCLUSION:For reliable results of TDM,it is necessary to implement good quality control of the assay to ensure that it contin...

关 键 词：治疗药物监测 色谱法 免疫分析法 

分 类 号：R452[医药卫生—治疗学]