110种藏药抗肿瘤体外筛选实验研究  

Antitumor Screening Research from 110 Tibetan Medicines

作　　者：宗玉英[1] 党合群[1] 骆桂法[1] 张幸福[1] 车镇涛[2] 

机构地区：[1]青海省药品检验所,西宁810000 [2]香港中文大学中医学院

出　　处：《药学实践杂志》2000年第5期290-291,共2页Journal of Pharmaceutical Practice

摘　　要：目的 :对 1 1 0种植物藏药进行抗肿瘤筛选。方法 :干燥植物样品粉碎后分别以石油醚及 90 %乙醇提取。用 90 %乙醇提取物对体外培养的 5种人体肿瘤细胞 :乳腺癌、肺癌、直肠癌、口腔上皮癌 (耐药性及非耐药性两种 )、前列腺癌及一种大鼠神经胶质肿瘤细胞进行筛选实验。结果 :有五种藏药 :桃儿七果实、藏木香、裸茎金腰、祁连圆柏、苍耳草具有较好的抗肿瘤作用。结论 :本研究对进一步研究、开发藏药提供科学的理论依据。OBJECTIVE:To screen antitumour medicine from 110 Tibetan medicines.METHODS:Dried plant materials were ground and were extracted by petrol ether and 90% ethanol separately.The 90% ethernal extracts were used to test cultured five human tumour cells:BC1,Lu1,Co12,KB and LNCaP and one rat tumour cell ASK.RESULTS:Five Tibetan medicines were found to display cytotoxic effects in cultured tumor cells.CONCLUSION:The result would be used as reference for further Tibetan medicine research.

关 键 词：抗癌筛选 藏药 

分 类 号：R285[医药卫生—中药学]