In vitro effect of danazol on the cytokine production ofperitoneal macrophages in patients with endometriosis  

作　　者：刘义 罗丽兰 赵海波 

出　　处：《生殖医学杂志》2000年第S1期34-36,共3页Journal of Reproductive Medicine

摘　　要：Objective: To study the effect of danazol in vitro on the cytokine production of peritoneal macrophages in patients with endometriosis. Methods: Peritoneal macrophages were obtained from 14 cases of patients with endometriosis. Danazol at concentration of 10 ng/ml and 100 ng/ml were added to the peritoneal macrophages cultures. The tumor necrosis factor a (TNFα)and interleukin 6 (IL-6) levels of peritoneal macrophage supernatant were detected by enzyme linked immunoassay. Results: Danazol at concentration of 100 ng/ml significantly inhibited TNFα and IL-6 production of peritoneal macrophages in patients with endometriosis. Conclusion: It is suggested that the immunomodulatory effect of danazol may contributed to the efficacy in the treatment of endometriosis.Objective: To study the effect of danazol in vitro on the cytokine production of peritoneal macrophages in patients with endometriosis. Methods: Peritoneal macrophages were obtained from 14 cases of patients with endometriosis. Danazol at concentration of 10 ng/ml and 100 ng/ml were added to the peritoneal macrophages cultures. The tumor necrosis factor a (TNFα)and interleukin 6 (IL-6) levels of peritoneal macrophage supernatant were detected by enzyme linked immunoassay. Results: Danazol at concentration...

关 键 词：ENDOMETRIOSIS DANAZOL Macropha$ 

分 类 号：R711.71[医药卫生—妇产科学]