Comparative Study on the Protective Effects of Yinchenhao Decoction(茵陈蒿汤) against Liver Injury Induced byα-Naphthylisothiocyanate and Carbon Tetrachloride  

作　　者：曹洪欣 孙晖 姜新刚 吕海涛 张广美 王喜军 孙文军 吴泽明 王萍 刘莲 周珏 

机构地区：[1]Department of Pharmacognosy Heilongjiang University of Chinese Medicine [2]China Academy of Chinese Medical Sciences [3]First Hospital Harbin Medical University

出　　处：《Chinese Journal of Integrative Medicine》2009年第3期204-209,共6页中国结合医学杂志（英文版）

基　　金：Supported by the Major State Basic Research Development Program of China(973 Program,No.2005CB523406)

摘　　要：Objective:To optimize the animal model of liver injury that can properly represent the pathological characteristics of dampness-heat jaundice syndrome of traditional Chinese medicine.Methods:The liver injury in the model rat was induced byα-naphthylisothiocyanate(ANIT) and carbon tetrachloride(CCl_4) respectively,and the effects of Yinchenhao Decoction(茵陈蒿汤,YCHD),a proved effective Chinese medical formula for treating the dampness-heat jaundice syndrome in clinic,on the two liver injury models were evaluate...Objective:To optimize the animal model of liver injury that can properly represent the pathological characteristics of dampness-heat jaundice syndrome of traditional Chinese medicine.Methods:The liver injury in the model rat was induced byα-naphthylisothiocyanate(ANIT) and carbon tetrachloride(CCl_4) respectively,and the effects of Yinchenhao Decoction(茵陈蒿汤,YCHD),a proved effective Chinese medical formula for treating the dampness-heat jaundice syndrome in clinic,on the two liver injury models were evaluate...

关 键 词：Yinchenhao Decoction α-naphthylisothiocyanate carbon tetrachloride liver injury dampness- heat jaundice syndrome 

分 类 号：R285.5[医药卫生—中药学]