单纯性肥胖儿童血清瘦素水平分析  

Analysis of Serum Leptin Levels in Children with Simple Obesity

作　　者：彭惠[1] 李丽文[1] 温天莲[1] 孙咏梅[1] 

机构地区：[1]山东大学医学院,山东省济南市中心医院儿科,250013

出　　处：《中国实用医药》2007年第6期1-2,共2页China Practical Medicine

摘　　要：目的分析单纯性肥胖儿童血清瘦素水平,探讨儿童肥胖发病机制。方法单纯性肥胖儿童33例,正常对照组43例,两组儿童均测标准身高、体重、计算体重指数(BMI),采用放射免疫分析法检测血清瘦索(leptin)水平。结果肥胖组儿童血清瘦素水平及BMI均值明显升高,与正常对照组间差异有显著性(P＜0．05)。结论单纯性肥胖儿童存在高瘦素血症,亦存在瘦素抵抗现象。Objective To analyze serum leptin levels in children with simple obesity,and to explore the pathogenesis of children obesity.Methods The observed were 33 cases of children with simple obesity, and the control were 43 cases of normal children.Both the two groups of children were measured the height, the weight,the BMI,and meatured the serum leptin concentration by radio immunoassay.Results The levels of serum leptin and BMI in obese group were dramatically higher than those in control group(P＜0.05).Con- clusion There was hyperleptinaemia in simple obesity children,and the simple obesity children had the phe- nomenon of leptin resistance.

关 键 词：单纯性肥胖 瘦素 瘦素抵抗 

分 类 号：R723[医药卫生—儿科]