腋臭单纯β线放射治疗的临床研究  

Clinical study of β line radiotherapy for bromhidrosis

作　　者：张新忠[1] 吴畏[1] 宋宏羽[1] 李黎军[1] 卜桂兰[1] 林运政[1] 

机构地区：[1]南方医科大学附属深圳宝安医院,深圳518101

出　　处：《中国实用医药》2007年第17期36-37,共2页China Practical Medicine

摘　　要：目的探索β线单纯放射治疗对腋臭大汗腺的抑制与破坏程度,气味改善,以及其量、效关系。方法126例病人应用西门子PRIMUS直线加速器、β线、6～9MeV、不同厚度生物等效膜,DT18～24Gy,大分割300～500cGy/(f.d)垂直照射,备皮后腋毛外缘外0.5～1.0cm设野,设定剂量参考深度:0.75-1.0-1.5-2.0cm。靶区DR约等于95%～100%。结合适形电子线Pb模,进行放射治疗。结果疗效:汗腺抑制,出汗少占90%(113/126);气味减轻改善为99%(124/126);臭味消失占90%(113/126);无效:2%(2/126)。不良反应:Ⅰ度局部皮肤急性放射性皮炎少见(<10%),25%(32/126)的患者有局部皮肤轻度色素沉着。结论单纯β线放射治疗腋臭可行、适用、有效。Objective To explore pure radiotherapy by β line for bromhidrosis and inhibitive and destructive degree for big sweat gland,odour improvement and relation between dose with effect.Methods 126 cases were treated by SIEMENS-PRIMUS accelerator,β line,6～9 MeV,different thickness for equivalent biomembrane,DT 18-24 Gy,big fraction 300～500 cGy/(f·d),vertical radiotherapy with reference dose deep:0.75-1.0-1.5-2.0 cm.Target's dose rate is about 95%～100%,combining radiotherapy under Pb mould.Results Effect:Sweat gland were inhibited about 90%(113/126),Odour lighten about 99%(124/126),Odour disappear about 90%(113/126),No avail 2%(2/126).Side effect:local acute radiodermatitis(Ⅰ)is a little(<10%),25%(32/126)cases have lightly local skin pigmentation.Conclusion Bromhidrosis by β line radiotherapy is feasible,applicable,effective.

关 键 词：腋臭 放射治疗 β线 生物等效膜 

分 类 号：R758.741[医药卫生—皮肤病学与性病学]