重型颅脑损伤早期应用胃肠内营养乳剂对低蛋白血症的防治效果分析  

Analyse the result for entogastric nutrition emulsion to reduce hypoproteinemia during early phase in heavy skull injure

作　　者：杨晓洪[1] 刘熙鹏[1] 

机构地区：[1]河北北方学院附属第一医院神经外科,张家口075000

出　　处：《中国实用医药》2007年第28期27-29,共3页China Practical Medicine

摘　　要：目的观察重型颅脑损伤早期(伤后48h～3周)使用胃肠内营养乳剂胃肠内营养支持对降低低蛋白血症发生的临床效果分析。方法选120例需肠内营养护理的重型颅脑损伤患者以不平衡指数最小的方法分为实验组:胃肠内营养乳剂组和对照组:自制均浆膳组,于受伤48h内分别开始使用胃肠内营养乳剂(瑞高)胃管注入护理和自制均浆膳胃管注入一般常规营养治疗,两种不同营养治疗持续期限均为21d,观察两组患者血清白蛋白(ALB)和血清总蛋白(TP)的动态变化。结果低蛋白血症实验组发生率3.4%,对照组发生率36.7%(χ2=54.2,P<0.01)。实验组明显低于对照组,ALB实验组为(38.1±6.77)g/L(t=4.05,P<0.01),对照组为(32.2±6.57)g/L(t=3.98,P<0.01),TP实验组为(71.8±8.28)g/L,对照组为(63.4±7.62)g/L,实验组明显高于对照组。实验组对预防和降低低蛋白血症的发生效果明显,与对照组相比可以显著降低低蛋白血症的发生。结论胃肠内营养乳剂早期应用对减少重型颅脑损伤后继发低蛋白血症有明确效果,值得推广应用。Objective To analyse the result for entogastric nutrition emulsion to reduce hypoproteinemia during early phase in heavy skull injure.Methods Choosed 120 heavy skull injure patients needed entogastric nutrition in our hospital and divided into 2 group(experimental group treated with entogastric nutrition emulsion and control group treated with self-made homogenic plasm)treated in 48 hours for 21 days,then observed the changement of ALB and TP.Results The ratio of hypoproteinemia was 3.4 percent in experimental group,36.7 percent in control group(χ2=54.2 P<0.01).The ratio of experimental group was magnificantly lower than that of control group.The ALB of experimental group was(38.1±6.77)g/L and(32.2±6.57)g/L in control group.The TP of experimental group was(71.8±8.28)g/L and(63.4±7.62)g/L in control group.The TP of level experimental group was distinctly higher than that of control group.Conclusion Using entogastric nutrition emulsion early to treat heavy skull injure patient can reduce hypoproteinemia.This method is worth to popularize.

关 键 词：胃肠内营养乳剂 重型颅脑损伤 胃肠内营养 低蛋白血症 

分 类 号：R651.15[医药卫生—外科学]