On-line matrix addition for detecting aerosol particles  

作　　者：ZHOU Liuzhu1,2, ZHU Yuan1, GUO Xiaoyong1, ZHAO Wenwu1, ZHENG Hai-yang1, Gu Xuejun1, FANG Li1 & ZHANG Weijun1 1. Lab of Environmental Spectroscopy, Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei 230031, China 2. Qufu Normal University, Qufu 273165, China 

出　　处：《Science China(Physics,Mechanics & Astronomy)》2006年第2期187-194,共8页中国科学：物理学、力学、天文学（英文版）

摘　　要：Single aerosol particles were measured by matrix-assisted laser desorp-tion/ionization (MALDI) with an aerosol time-of-flight mass spectrometer (ATOFMS). The inlet to the ATOFMS was coupled with an evaporation/condensation flow cell that allowed matrix addition by condensation onto the particles. The coated particles entered the ion source through three-stage differentially pumped capillary inlet and were then ionized by a focused 266 nm Nd:YAG laser. The mass spectra and aerodynamic size of the single particles can be obtained simultaneously. The on-line matrix addition technique makes it possible to identify biological aerosols in real-time.Single aerosol particles were measured by matrix-assisted laser desorp-tion/ionization (MALDI) with an aerosol time-of-flight mass spectrometer (ATOFMS). The inlet to the ATOFMS was coupled with an evaporation/condensation flow cell that allowed matrix addition by condensation onto the particles. The coated particles entered the ion source through three-stage differentially pumped capillary inlet and were then ionized by a focused 266 nm Nd:YAG laser. The mass spectra and aerodynamic size of the single particles can be obtained simultaneously. The on-line matrix addition technique makes it possible to identify biological aerosols in real-time.

关 键 词：ATOFMS evaporation/condensation MALDI. 

分 类 号：O657.63[理学—分析化学]