Hydrogen peroxide homeostasis and signaling in plant cells  

作　　者：CHENG Yanli SONG Chunpen 

机构地区：[1]Laboratoryof Plant Stress Biology, Department of Biology, Henan University, Kaifeng 475001, China Laboratoryof Plant Stress Biology, Department of Biology, Henan University, Kaifeng 475001, China

出　　处：《Science China(Life Sciences)》2006年第1期1-11,共11页中国科学（生命科学英文版）

基　　金：supported by the National Natural Science Foundation of China(Grant Nos.39870372,30370765&30440079);the National Key Basic Special Funds(Grant No.2003CB114305).

摘　　要：The increases of H2O2 concentrations in plant cells often occur under biotic and abiotic stress conditions (e.g. light, environmental stresses and plant hormone abscisic acid). Atmospheric H2O2 as an ancient signal molecule not only plays the key role in inducing evolution of oxygenic photosynthesis, but also modulates many physiological events, such as stomatal movement, hypersensitive responses, programmed cell death and gene expressions. H2O2 levels in cells must sustain a fine equilibrium between production and scavenging. H2O2 enters cells from the apoplast or generated sources, and in turn is distributed in sub-cellular compartments. H2O2 can modulate the activities of many components in signaling, such as protein phosphatases, protein kinases, transcription factors (TFs), and calcium channels. Elevated cytosolic calcium concentrations will initiate further downstream responses, via the action of calcium-binding proteins. On the other hand, the research of H2O2 as a signal molecule is still in a comparatively juvenile stage, for example, little is known about how the cells sense H2O2, what the rate-limiting steps and most important cellular events are in cell signaling and what kind of genes is specific or necessary to H2O2 signaling. The answers to all the questions depend on the functional genomic and molecular genetics analysis.The increases of H_2O_2 concentrations in plant cells often occur underbiotic and abiotic stress conditions (e.g. light, environmental stresses and plant hormone abscisicacid). Atmospheric H_2O_2 as an ancient signal molecule not only plays the key role in inducingevolution of oxygenic photosynthesis, but also modulates many physiological events, such as stomatalmovement, hypersensitive responses, programmed cell death and gene expressions. H_2O_2 levels incells must sustain a fine equilibrium between production and scavenging. H_2O_2 enters cells fromthe apoplast or generated sources, and in turn is distributed in sub-cellular compartments. H_2O_2can modulate the activities of many components in signaling, such as protein phosphatases, proteinkinases, transcription factors (TFs), and calcium channels. Elevated cytosolic calciumconcentrations will initiate further downstream responses, via the action of calcium-bindingproteins. On the other hand, the research of H_2O_2 as a signal molecule is still in a comparativelyjuvenile stage, for example, little is known about how the cells sense H_2O_2, what therate-limiting steps and most important cellular events are in cell signaling and what kind of genesis specific or necessary to H_2O_2 signaling. The answers to all the questions depend on thefunctional genomic and molecular genetics analysis.

关 键 词：H2O2  signal transduction  abscisic acid  environmental stresses  gene expression  apoptosis. 

分 类 号：N[自然科学总论]