糖尿病性周围神经病的临床与电生理改变  

Clinical and Electrophysiological Changes of Diabetic Perineuropathy

作　　者：陆勤[1] 金嘉翔[1] 李威[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院神经内科,上海200011

出　　处：《神经病学与神经康复学杂志》2006年第1期25-27,30,共4页Journal of Neurology and Neurorehabilitation

摘　　要：目的探讨糖尿病性周围神经病的电生理特点及其诊断价值。方法检测52例2型精尿病患者与50例正常人肌电图进行对照统计分析。结果观察组中确诊为临床或亚临床周围神经病的共41例(78.85%)。观察组的正中神经、尺神经、胫后神经、腓总神经、腓肠神经传导速度(NCV)及波幅(AMP)明显低于正常对照组。各神经传导速度与糖尿病病程及糖化血红蛋白(HbA_1c)水平呈负相关,观察组中合并正中神经腕管卡压者明显高于一般人群。结论神经电生理检查能一定程度地反映糖尿病患者的周围神经受损程度。Objective To investigate the electrophysiological features and dignostic value of perineuropathy in patients with type Ⅱ diabetes mellitus. Methods The resuhs of electrogram between 52 cases of type Ⅲ diabetes mellitus and 50 controls were compared and analysed statistically. Results Forty-one cases(78.85% ) were confirmed as clinical or subclinical perineuropathy in the observation group. The nerve conduction velocities(NCV) and wave amplitudes of the median nerve, ulnar nerve, posterior tibial nerve, common peroneal nerve, and sural nerve in the observation group were markedly lower than those in the control group( P<0.01). There were significant negative correlations between nerve conduction velocity and diabetic duration and the level of HbA_1c. The occurrence rate of carpal tunnel syndrome in diabetics was higher than that in the control group. Conclusion Electrophysiological examination can sensitively assess the injured degrees of peripheral nerves in diabetics.

关 键 词：糖尿病性周围神经病 神经传导速度 病程 糖化血红蛋白 腕管卡压综合征 

分 类 号：R587.2[医药卫生—内分泌] R745.1[医药卫生—内科学]