高血压合并脑梗死患者血浆C-反应蛋白、纤维蛋白原及白细胞变化的研究  

Plasma C-reactive Protein,Fibrinogen and Plasma Leukocytes in Essential Hypertension Patients with Ischemic Stroke

作　　者：邓远飞[1] 杭娟[1] 陈延娥[1] 

机构地区：[1]北京大学深圳医院干部病房,深圳市518032

出　　处：《中国卒中杂志》2006年第8期551-553,共3页Chinese Journal of Stroke

摘　　要：目的探讨高血压合并脑梗死患者急性期血浆C-反应蛋白(CRP)、纤维蛋白原(Fib)水平、白细胞(WBC)及分类计数的变化与高血压合并脑梗死的关系。方法将患者分为两组,高血压合并脑梗死组(68例)和单纯高血压组(65例),检测两组患者急性期血浆CRP、Fib和WBC水平。结果高血压合并脑梗死患者急性期CRP、Fib水平、WBC总数、中性粒细胞数均比单纯高血压患者明显增高(P＜0．01)。结论C-反应蛋白、纤维蛋白原和白细胞升高可能与脑梗死的发生和进展相关,抗炎治疗可能是脑梗死治疗的一个选择。Objective To study the changes and relationships of C-reactive protein(CRP),fibrinogen concentra- tions,plasma Leukocytes(WBC)and its differential count in essential hypertension patients with ischemic stroke.Methods We recruited 68 patients who had essential hypertension with ischemic stroke,and 65 patients who had simple essential hyperten- sion as controls.The concentrations of Plasma CRP and fibrinogen and the count of WBC were measured for all the patients.Re- sults The plasma CRP and fibrinogen concentrations,WBC and its differential count increased significantly(P＜0.01)in is- chemic stroke group comparing to the simple essential Hypertension group.Conclusion Inflammatory reaction may be one of the important dangerous factors of the occurrence and progression of cerebral intarction;Relieving inflammation may help to prevent cerebral infarction and improve the prognosis of it.

关 键 词：高血压 脑梗死 C-反应蛋白 纤维蛋白原 

分 类 号：R544.1[医药卫生—心血管疾病] R743.3[医药卫生—内科学]