组织多普勒显像与冠脉造影对缺血心肌舒张功能的评价  

Evaluation of regional diastolic function in ischemic myocardium with tissue doppler imaging and angiography of coronary artery

作　　者：王文清[1] 刘金耀[1] 郭华朝[1] 王新宴[1] 宁波[1] 石津生[1] 杜军[1] 刘波[1] 

机构地区：[1]空军总医院老年病科,北京100036

出　　处：《空军总医院学报》2001年第2期73-75,共3页Journal of General Hospital of Air Force,PLA

摘　　要：目的　本文与冠状动脉造影对照研究组织多普勒显像 (TDI)技术评估缺血心肌局部舒张功能的价值。　方法　超声心动图记录心肌缺血 (Is,2 8例 )和志愿者 (Con,30例 )舒张期二尖瓣血流频谱 (TMF)及左室基底部 ,中部和心尖部三个水平面 15节段 TDI。　结果　两组间左室射血分值相近 ;Is组 TMF舒张早期减速度时间和等容舒张时间延长 (P<0 .0 1) ;E/A比值增加 (P<0 .0 1) ;Con组 TDI示左室基底部与中部心肌舒张早期舒张速度 (m E)高于心尖部 (P<0 .0 5 ) ,缺血节段 m E降低 ,局部早期舒张减速度时间和等容舒张时间延长 ;Is组异常显示率 TDI高于 TMF(93% :6 4% ,P<0 .0 1)。　结论　 TDI可无创检测左室局部舒张功能 ,其异常显示率高于Objective We evaluated the ability of tissue Doppler imaging(TDI), a new echocardiographic techique that can image the regional myocardial velocity, to assess the regional diastolic function in ischemic heart disease. Methods Control subjects (Con,30 cases)and patients with ischemic heart diseases(IS,28 cases)were enrolled.Global and regional isovalumic relaxation time(IRT,mIRT),deceletation time of early filling (DcT, mDcT),early diastolic velocity(E,mE), late diastolic velocity (A, mA),E/A and mE/mA were measured by pulsed Doppler echocardiography and TDI respectively. Results There were not difference in LVEF between Is and Con groups. Compared with Con, DcT and IRT were prolonged ( P <0.001) in Is group respectively. The mE in basal and middle level of left ventricle were higher than those in apical level in Con group. The slower mE, longer mIRT and rmDcT were found in Is segments. Compared to diastolic transmitral flow,TDI showed higher abnormal rate in Is group(64% vs 93%, P <0.01). Conclutions TDI can non invasive evaluate of regional diastolic function in ischemic myocardium,which showed abnormal relaxation pattern and more sensitive than TMF.

关 键 词：超声心动描记术 多普勒 心室功能 左 心肌缺血 冠状血管造影术 

分 类 号：R540.45[医药卫生—心血管疾病] R331.31[医药卫生—内科学] R542.2[医药卫生—临床医学] R816