米非司酮治疗异位妊娠后宫内再孕率分析  

Analysis of secondary pregnancy rate after treatment of ectopic pregnancy with mifepristone

作　　者：高慧莉[1] 罗珂[2] 

机构地区：[1]北京大学首钢医院妇产科,100041 [2]宁夏医学院第二附属医院妇产科

出　　处：《中国妇产科临床杂志》2003年第6期443-444,451,共3页Chinese Journal of Clinical Obstetrics and Gynecology

摘　　要：目的　探讨米非司酮 (RU4 86 )治疗异位妊娠成功后的宫内再孕率。方法　回顾性分析我院1 996年 1月～ 2 0 0 2年 1月之间收治的 98例有生育要求的、药物保守治疗成功的异位妊娠患者的临床资料 ,其中5 8例为米非司酮 (RU4 86 )治疗成功 ,4 0例为甲氨蝶呤 (MTX)全身治疗成功 ,并经门诊及电话随诊。结果　RU4 86治疗者宫内再孕率 5 1 7% ,MTX治疗者宫内再孕率 5 2 5 % ,两者比较差异无显著性 (P >0 0 5 )。结论　RU4 86保守治疗的宫内再孕率和MTX保守治疗的宫内再孕率比较无明显差异 ,而且前者无明显副作用 ,血 β -hCG下降明显 。Objective To investigate the pregnancy rate after treatment of ectopic pregnancy with the mifepristone (RU486). Methods From January 1996 to January 2002, 98 women with confirmed ectopic pregnancy and desiring to conceive were successfully treated either with systemic MTX (58), or with mifepristone (40). All were followed up by outpatient service and telephone. Results The rates of subsequent intrauterine pregnancies (IUP) in the RU486 group and MTX group were 51 7% (30/58) and 52 5%(21/40) respectively, with no statistical difference. Conclusions The effect of conservative management with RU486 is similar to MTX, yet the former presents no significant side-effect, quick decreasing of sera β-hCG, and is more acceptable for patients.

关 键 词：异位妊娠 米非司酮 妊娠率 

分 类 号：R714.2[医药卫生—妇产科学]