呋喃甲酰基吡唑啉酮缩氨基硫脲稀土配合物的合成、表征及生物活性  

Synthesis,Characterization and Bioactivity of Rare Earth Complexes of Furoylpyrazolone-thiosemicarbazne

作　　者：李锦州[1] 沙靖全[1] 安郁美[1] 于文锦[1] 

机构地区：[1]哈尔滨师范大学化学系,黑龙江哈尔滨150080

出　　处：《中国稀土学报》2002年第z3期10-13,共4页Journal of the Chinese Society of Rare Earths

基　　金：黑龙江省自然科学基金(B01-06);黑龙江省高校骨干教师创新计划资助项目

摘　　要：合成了含硫席夫碱试剂1 苯基 3 甲基 4 (( 呋喃甲酰基)吡唑啉酮 5缩氨基硫脲(L)及其10种稀土配合物。元素分析及摩尔电导值表明新配合物的组成为[REL2(NO3)2]NO3(RE=La,Pr,Nd,Sm,Eu,Tb,Dy,Er,Yb,Y。运用红外光谱、紫外光谱、核磁共振谱和荧光光谱对配合物进行了表征。抗菌实验表明配合物具有较强的抗菌生物活性。A new Schiff base containing sulphur, 1phenyl3methyl4(αfuroyl) pyrazolone5thiosemicarbazne (L) and its ten rare earth complexes were synthesized. On the basis of elemental analysis and molar conductance, the general formula of the complexes, NO3 (RE = La, Pr, Nd, Sm, Eu,Tb,Dy, Er, Yb,Y), was given. They were characterized by IR, UV-visible, 1H NMR ,13C NMR and fluorescence. The results show that the rare earth ions exhibit coordination of eight in the complexes. The antibacterial experiments indicate that they have high antibacterial activities against S. aureus, B. subtillis, E. coli, E.carotovora, and C. flaccumfaciens.

关 键 词：稀土 呋喃甲酰基吡唑啉酮 氨基硫脲 配合物 生物活性 

分 类 号：O614.33[理学—无机化学] O626.21[理学—化学]