嗜酒者血清胆汁酸、透明质酸、Ⅳ型胶原、γ-谷氨酰转肽酶测定及其临床意义  

Measurement of alcoholic addicted person's serum TBA, HA, Ⅳ·C, γ-GT and its Clinical significance

作　　者：程薇莉[1] 宗鲜[1] 赵美林[1] 丁茗敏[1] 张桂兰[1] 王淑勤[1] 陈瑛[1] 

机构地区：[1]解放军济南军区青岛第一疗养院,山东青岛266071

出　　处：《临床军医杂志》2000年第1期41-43,共3页Clinical Journal of Medical Officers

摘　　要：目的　测定血清胆汁酸 (TBA)、透明质酸 (HA)、Ⅳ型胶原 (Ⅳ·C)、γ 谷氨酰转肽酶 (γ GT)、碱性磷酸酶 (ALP)、丙氨酸转氨酶 (ALT)含量以探讨其在乙醇性肝细胞损伤早期诊断中的价值。方法　TBA采用Randox公司生产的酶法测定试剂盒 ,HA ,Ⅳ·C应用放射免疫分析法 ,γ GT ,ALP ,ALT采用生化分析仪测定。结果　血清TBA ,HA ,γ GT含量明显高于对照组 (P均 <0 .0 0 1) ;Ⅳ·C ,ALP ,ALT无显著性变化。结论　血清TBA ,HA ,γ GT含量测定在嗜酒者肝脏损伤的早期诊断中具有良好应用价值。Objective To study the applicable value of total bile acids(TBA), hyaluronic acid(HA), type Ⅳ collagen(Ⅳ·C),γ Glutamyltransferase(γ GT), aldaline phorphatase(ALP), ALT in the detection of initial diagnosis of liver disease of alcoholic addicted persons Method TBA was studied using Regent kit produced by Randox corporate and HA, Ⅳ·C using radioimmunological analysis and γ GT, ALP, ALT using Biochemistry Analyzer Result TBA, HA, γ GT were markedly increased in alcoholic addicted persons( P <0.001)and Ⅳ·C, ALT, ALT had no significant change compared with the healthy controls Conclusion TBA, HA and γ GT contents are of good applicable value in initial diagnosis of liver disease in alcoholic addicted persons

关 键 词：嗜酒者 胆汁酸 透明质酸 Ⅳ型胶原 Γ-谷氨酰转肽酶 乙醇 

分 类 号：Q592.1[生物学—生物化学]