心绞痛高位胸段硬膜外阻滞治疗及内皮素含量变化  

ET-1 Changes in Angina Pectoris Treatment by High-positioned Thoracispinal Epidural Anesthesia

作　　者：陈国忠[1] 孙淑清[2] 李中言[3] 李学[1] 曹凤绮[3] 董红红[4] 

机构地区：[1]吉林军医学院附属医院麻醉科,吉林吉林132013 [2]吉林军医学院附属医院泌尿外科,吉林吉林132013 [3]吉林军医学院附属医院心肾内科,吉林吉林132013 [4]空军后勤学院,江苏徐州221000

出　　处：《第四军医大学吉林军医学院学报》2001年第2期80-81,共2页

摘　　要：目的　观察高位胸段硬膜外阻滞 (TEA)对顽固性心绞痛 (FAP)患者的治疗效果及其对内皮素 (ET 1)的影响。方法　选择药物不能控制的心绞痛患者 2 0例接受TEA治疗 ,观察疗效及治疗前、后血浆ET 1的变化。结果　治疗后心绞痛缓解率 10 0 % ,心电图ST段压低导联数和ST压低值显著减少 (P <0 .0 5 ) ,血浆ET 1显著下降 (P <0 .0 1)。Objective To observe the effect of high positioned TEA on FAP and ET 1.Methods Twenty cases with refractory angina pectoris were chosen to receive TEA treatment for observation of therapeutic effect and serum ET 1 changes before and after treatment.Results Remission rate of angina pectoris was 100 %.Depressed lead of S T segment and S T depressed value significantly decreased( P <0.05)and serum ET 1 was greatly reduced ( P <0.01).Conclusion TEA has a good therapeutic effect on FAP.

关 键 词：硬膜外阻滞 心绞痛 内皮素 

分 类 号：R614[医药卫生—麻醉学]