尿液CysC检测评价肾小管损伤的价值  

Assessment of Renal Tubular Function with Urinary Content of Cystatin C

作　　者：吴祥林[1] 

机构地区：[1]安徽省铜陵市人民医院检验科,安徽铜陵244000

出　　处：《医学检验与临床》2008年第2期42-43,67,共3页Medical Laboratory Science and Clinics

摘　　要：目的探讨尿半胱氨酸蛋白酶抑制剂C(CysC)用于评价早期肾小管损伤的价值。方法用免疫增强比浊法测定CysC,用ELISA法测定RBP,用化学比色法测定NAG。结果异常检出率CysC为56.7%,RBP为53.3%,NAG为66.7%。CysC与RBP相关有显著性(r=0.752,p<0.01),与NAG无相关性(r=0.95,p>0.05)。结论尿CysC是诊断早期肾小管损伤的有效指标。Objective Study on the relationship between renal tubular function and urinary cystatin C(CysC).Methods The concentration of urinary CysC was detected with latex particle-enhanced nephelometric immunoassay,the level of RBP was determined with enzyme linked immunoad assay,and the volume of NAG was investigated by biochemical test.Results The positive rate,CysC was 56.7%,RBP was 53.3%,NAG was 66.7%.There was a correlation between urinary CysC and RBP,(r=0.752,p<0.01).Conclusion CysC could be as a valuable index for the assessment of renal tubular function.

关 键 词：半胱氨酸蛋白酶抑制剂C 肾小管损伤 N-乙酰-Β-D氨基葡萄糖苷酶 尿视黄醇结合蛋白 

分 类 号：R446.6[医药卫生—诊断学]