维族与汉族强直性脊柱炎患者炎性指标的差异性分析  

Differences of Inflammation Indices in Uygur and Han Patients with Ankylosing Spondylitis

作　　者：廖朗[1] 郭跃文 杨忠礼[3] 商建然 

机构地区：[1]新疆生产建设兵团农13师哈密红星医院检验科,新疆839001 [2]新疆哈密地区第二人民医院检验科,新疆839001 [3]新疆自治区人民医院临床检验中心,新疆830001 [4]新疆哈密地区第二人民医院儿科,新疆839001

出　　处：《医学检验与临床》2008年第3期93-94,139,共3页Medical Laboratory Science and Clinics

摘　　要：目的初步探讨维族与汉族强直性脊柱炎患者炎性指标间的差异性。方法对49例维族和87例汉族强直性脊柱炎患者进行外周血炎性指标检测。结果分析显示维族和汉族AS患者性别构成存在统计学差异(x2=8.36,P=0.0038),维族患者男性比率(93.88%)明显高于汉族(73.56%),而不同年龄段性别构成均无统计学差异(x2维族=0.65,P=0.7214;x2汉族=3.38,P=0.1836);维族与汉族儿童青少年(20.41%,10.34%)和青壮年(67.35%,80.46%)患者比率均无统计学差异(x2=2.64,P=0.1041;x2=2.93,P=0.0868);血清超敏C反应蛋白(hsCRP)和CRP存在统计学显著性差异(thsCRP=2.36,P=0.0193;tCRP=4.08,P=0.0001),均表现为维族患者检测水平明显高于汉族,ASO检测水平在正常值范围内表现出维族患者高于汉族(t=8.13,P=0.0000)。白细胞计数(WBC)在正常值范围内民族间无差异(t=0.97,P=0.3323),而单核细胞水平(#MONO)维族患者明显高于汉族(t=2.23,P=0.0255),且其单核细胞升高比率(91.8%)亦明显高于汉族(60.9%)患者(x2=14.88,P=0.0001)。结论维族与汉族强直性脊柱炎患者炎性指标间存在一定程度的差异性,有待于进一步深入研究。Objective To discuss difference of inflammation indices in Uygur and Han patients with Ankylosing Spondylitis(AS).Methods The inflammation indices were detected to samples of 49 Uygur and 87 Han patients.Results Analysis showed sex constitution existed statistic difference between Uygur and Han patients with AS(x2=8.36,P=0.0038),male ratio of Uygur patient(93.88%) was more higher than that of Han(73.56%),but non-difference were found in sex constitution among different age section(x2(Uygur)=0.65,P=0.7214;x2Han =3. 38 ,P = 0. 1836) . Ratio of children (20.41% ,10. 34%) and young adults( 67. 35 % ,80. 46%) had no difference respectively between Uygur and Han patients (x^2 = 2.64,P=0.1041;x2=2.93 ,P=0.0868).Serum hsCRP and CRP levels were found significant difference (thsCRP = 2.36,P=0.0193;tCRP=4.08,P=0.0001) and showed Uygur higher than Han patient , ASO levels displayed Uygur higher than Han patient (t=8.13,P=0.0000) in normal reference.WBC counts had no difference between nationalities in normal references (t=0.97,P=0.3323) ,while mononuclear cell counts of Uygur was more higher than that of Han (t=2.23,p=0.0255) and its positive ratio of Uygur (91.8%) also higher than that of Han (60.9%)(x^2=14.88 ,P=0.0001) . Conclusions The inflammation indices has certain degree difference between Uygur and Han patients with AS ,and waits to further thoroughly studies.

关 键 词：民族 强直性脊柱炎 炎性指标 差异性 

分 类 号：R593.23[医药卫生—内科学]