血清半胱氨酸蛋白酶抑制剂C在二型糖尿病肾病早期的应用价值  

Application of Cystatin C in early nephrosis of type 2 diabetic patients

作　　者：黄晓华[1] 卢丽珊[1] 

机构地区：[1]福建省龙岩市第一医院检验科,福建龙岩364000

出　　处：《医学检验与临床》2008年第5期42-43,共2页Medical Laboratory Science and Clinics

摘　　要：目的探讨血清胱抑素C(CystatinC)在糖尿病肾病早期诊断中的临床意义。方法采用乳胶颗粒增强免疫比浊法(TPNIA)测定51例糖尿病患者血清胱抑素C,同时测定血肌酐(SCr,酶法)及肌酐清除率(CCr),比较CystatinC,SCr与CCr的相关性。结果血清CystatinC,SCr与CCr与糖尿病肾病均呈显著相关,其中以Cystatinc与CCr的相关程度最为密切。结论CystatinC在糖尿病肾病早期诊断中具有较高的准确性。能可靠地反映肾功能早期损害的指标,在糖尿病肾病的早期诊断中具有指导意义。Objective To assss the clinical significance of Cystatin C as earlykidney in type 2 diabetic patients.Methods The particle-enhanced immunonephrometic assay was used in Cystatin C in type 2 diabetic patients.and determined serum creatinine(Scr)、CCr,compared the correlated between Cystatin C,SCr or CCr.Results Cystatin C,Scr,CCrwere all correlated significantly with 2 diabetic patients wth kidney.Conclusion Cystatin C is more accurate and is better markers in reflecting the early of renal function of 2 diabetic patients.

关 键 词：糖尿病肾病 血清胱抑素C 肌酐清除率 

分 类 号：R587.2[医药卫生—内分泌]