持续正压通气、等离子消融和改良腭咽成形术综合治疗重症阻塞性睡眠呼吸暂停综合征  

Airway Pressure,Plasma Radiofrequency Ablation and Modified Uvuopalatopharyngoplasty Treat Severe Obstructive Sleep Apnea Syndrome

作　　者：李正贤[1] LUDN VJ 

机构地区：[1]解放军第163医院耳鼻咽喉科,长沙410003 [2]Institute of Laryngology and Otology at University College London

出　　处：《湖南师范大学学报（医学版）》2005年第2期33-36,共4页Journal of Hunan Normal University(Medical Sciences)

摘　　要：目的:探讨重症阻塞性睡眠呼吸暂停低通气综合征的治疗方法,提高临床疗效和减少并发症.方法:对15例经多导睡眠监测仪监测确认为重症阻塞性睡眠呼吸暂停低通气综合征患者术前进行为期1 W的持续正压通气,再进行改良腭咽成形和等离子软腭、悬雍垂、舌根及下鼻甲消融,扩大咽气道.结果:术后随访3～6 m,无明显并发症,所有患者均取得了满意效果.患者射频治疗前和治疗12W后多导睡眠参数比较显示:治疗后Ⅰ+Ⅱ期睡眠时间明显缩短,Ⅲ+Ⅳ期睡眠时间明显延长,睡眠效率及最低脉氧饱和度(LspO2)均显著提高(P＜0.01);呼吸暂停低通气指数减低及打鼾时间缩短均较治疗前相比差异非常显著(P＜0.01).患者射频治疗12 W后软腭长主及悬雍垂度的缩短及鼾声评级的降低均较治疗前相差非常显著(P＜0.01).Epworth嗜睡程度评分亦较治疗前明显降低(P＜0.01).结论:持续正压通气、腭咽成形术和等离子消融综合治疗阻塞性睡眠呼吸暂停低通气综合征具有较好的近期疗效,且方便、安全、微创、恢复快,无不良反应,有较好的发展前景,值得推广应用.Objective To investigate the therapy methods,improve the clinical efficacy and reduce the complications on severe obstructive sleep apnea syndrome(OSAS).Methods 15 patients with polysomnographically proven serious obstructive sleep apnea hypopnea syndrome were given continue positive airway pressure for 1 week before plasma radiofrequency ablation to uvula,tongue base,soft palate and inferior turbinates and modified uvuopalatopharyngoplast enlarged oropharyngeal air duct.The polysomnography examinations wer...

关 键 词：重型的 阻塞性睡眠呼吸暂停综合征 持续正压通气 腭咽成形术 等离子射频消融术 

分 类 号：R766[医药卫生—耳鼻咽喉科]