转化生长因子β1与绝经后妇女高血压的相关性研究  

The Correlative Study of Serum TGF-β_1 Concentration and Hypertension on Postmenopausal Eomen

作　　者：于才红[1] 吕爱莲[2] 符晓华[1] 张娜[1] 彭小宁[1] 张勇[1] 

机构地区：[1]湖南师范大学医学院,湖南长沙410006 [2]长沙市一医院心内科,湖南长沙410005

出　　处：《湖南师范大学学报（医学版）》2006年第4期13-14,20,共3页Journal of Hunan Normal University(Medical Sciences)

基　　金：湖南省卫生厅科学基金资助项目(C2003-017)

摘　　要：目的:探讨绝经后女性高血压组和正常血压组之间转化生长因子β1的分布及两组之间有无区别。方法:用ELISA法测定绝经后有高血压和血压正常组女性的血清TGF-β1的水平。结果:血压正常组血清TGF-β1浓度为(25.5±10.4)ng/mL,而高血压组其浓度为(29.1±12.4)ng/mL,两组差异有显著性(P<0.05);而且血清TGF-β1水平与舒张压有相关性,与收缩压无相关。结论:血清TGF-β1水平的升高可能是绝经后女性高血压发病率增高的一个非常重要的影响因素。Objective To explore the distribution and difference of TGF-β_1 in postmenopausal women with normal blood pressure and with hypertension.Mothods To measure the levels of TGF-β_1 by ELISA testing kits purchased from DRG GmbH company in Germany.Results Serum levels of TGF-β in postmenopausal women with normal blood pressure was(25.5±10.4)ng/mL,while in women with hypertension the level was(29.1±12.4)ng/mL.There was significant difference between the two groups.②Distolic blood pressure was negatively correlate...

关 键 词：转化生长因子 绝经 女性 高血压 

分 类 号：R544.1[医药卫生—心血管疾病]