Design and testing of micro fluidic chemical analysis chip integrated with micro valveless pump  

作　　者：FU Xin XIE Haibo YANG Huayong JIA Zhijian FANG Qun 

机构地区：[1]State Key Laboratory of Fluid Power Transmission and Control,Zhejiang University,Hangzhou 310027,China State Key Laboratory of Fluid Power Transmission and Control,Zhejiang University,Hangzhou 310027,China State Key Laboratory of Fluid Power Transmission and Control,Zhejiang University,Hangzhou 310027,China Institute of Microanalytical Systems,Zhejiang University,Hangzhou 310028,China Institute of Microanalytical Systems,Zhejiang University,Hangzhou 310028,China

出　　处：《Science China(Technological Sciences)》2005年第3期326-337,共12页中国科学（技术科学英文版）

基　　金：This work was supported by the National Natural Science Foundation of China(Grant Nos.50335010,50175098).

摘　　要：A new structure and working principle of the chip integrated with micro valveless pump for capillary electrophoresis was proposed in this paper. The micro valveless pump with plane structure has advantages of simple structure, and the process technology is compatible with existing micro chips for capillary electrophoresis. Based upon the mathematical model, simulation study of micro pump was carried out to investigate the influence of structural parameters on flow characteristics, and the performance of the integrated micro pump was also tested with different control parameters. The simulation results agree with the experimental results. Three samples, which are amino acid, fluorescein and buffer solution, have been examined with this chip. The results of the primary experiments showed that the micro valveless pump was promising in the integration and automatization of miniature integrated fluidic systems.A new structure and working principle of the chip integrated with micro valveless pump for capillary electrophoresis was proposed in this paper. The micro valveless pump with plane structure has advantages of simple structure, and the process technology is compatible with existing micro chips for capillary electrophoresis. Based upon the mathematical model, simulation study of micro pump was carried out to investigate the influence of structural parameters on flow characteristics, and the performance of the integrated micro pump was also tested with different control parameters. The simulation results agree with the experimental results. Three samples, which are amino acid, fluorescein and buffer solution, have been examined with this chip. The results of the primary experiments showed that the micro valveless pump was promising in the integration and automatization of miniature integrated fluidic systems.

关 键 词：MEMS micro valveless pump micro fluidic chip CFD capillary electrophoresis. 

分 类 号：TH[机械工程]