复合式人工鼻过滤器对下呼吸道医院感染 防控作用的观察研究  

NOSOCOMIAL LOWER RESPIRATORY TRACT INFECTION IN INTENSIVE CARE UNIT: A STUDY AND INVESTIGATION OF B/VF-HME's INTERVENTION EFFECT

作　　者：李素晓[1] 张玉英[1] 张立志[1] 张莉娟[1] 杭景仙[1] 刘甲俊[1] 

机构地区：[1]河北省人民医院医院感染管理科,河北石家庄050051

出　　处：《河北医科大学学报》2009年第8期801-803,共3页Journal of Hebei Medical University

基　　金：2005年河北省科技厅计划课题(52761747)

摘　　要：目的探讨针对重症监护病房(intensive care unit,ICU)有创通气患者下呼吸道医院感染(nosocomiallower respiratory tract infection,NLRTI)的控制措施,以控制ICU住院患者NLRTI率。方法对2005年-2007年入住ICU的患者,随机筛选年龄、性别、病情相近的2组各72例有创通气患者进行前瞻性调查,使用复合式人工鼻过滤器(bacterial/viral filter-heat and moisture exchanger,B/VF-HME)患者为干预组,同时观察过滤膜两侧的微生物附着情况;另1组有创通气不用B/VF-HME的患者为对照组。调查资料采用SAS 6.12Logistic程序进行统计分析。结果有创通气加B/VF-HME患者的NLRTI发病率低,2组差异有统计学意义(P<0.01)。过滤膜两侧皆有微生物生长,既有呼吸道条件致病菌,又有正常菌群。结论综合ICU有创通气患者中加用B/VF-HME是控制NLRTI的有效措施之一。Objective To explore the controlling measure of nosocomial lower respiratory tract infection(NLRTI) in intensive care unit(ICU) and to control its NLRTI rate.Methods A prospective study was done on 144 patients hospitalized in ICU from 2005 to 2007,which was divided into two groups randomly according to their age,sex,disease's condition.Bacterial/Viral Filter- Heat and Moisture Exchanger (B/VF-HME) was used in intervention group and the control group didn't use it.SAS 6.12 Logistic software was used in the study.Results The rate of NLRTI in patients with injured machanical ventilation used B/VF-HME was decreased.The difference was significant between the two groups,and bacterium was cultured in the samples of the two sides of the filter,including respiratory tract normal flora and conditional pathogenic bacteria.Conclusion The studies showed using B/VF-HME was one of the key measures to control NLRTI for patient with injured machanical ventilation in ICU.

关 键 词：交叉感染 呼吸道感染 重症监护病房 

分 类 号：R563[医药卫生—呼吸系统] R372[医药卫生—内科学]