硬膜外布托啡诺用于老年患者髋关节置换术后镇痛  

Epidural butorphanol analgesia in elderly patients undergoing hip replacement

作　　者：胡冬华[1] 李雅兰[1] 蔡明雪[1] 张惠[1] 项明方[1] 帅兵[1] 聂偲[1] 

机构地区：[1]暨南大学第一临床医学院麻醉教研室,广东广州510630

出　　处：《南方医科大学学报》2009年第7期1435-1437,共3页Journal of Southern Medical University

摘　　要：目的观察布托啡诺持续硬膜外输注镇痛用于老年病人髋关节置换术后的临床效应及安全性。方法60例年龄60～103岁,ASAI～II级的择期髋关节置换术患者,术毕随机分为两组,使用一次性镇痛泵分别用布托啡诺(B组,n=30例)和吗啡(M组,n=30例)持续输注镇痛。观察术后4、8、12、24、48h患者的疼痛程度,患者对镇痛治疗总体印象评分以及不良反应。结果B组与M组术后不同时间点镇痛效果比较差异无显著性(P>0.05),但是术后48h内B组不良反应(呼吸抑制、恶心、呕吐、瘙痒、腹胀等)比M组少(P<0.01)。结论布托啡诺持续硬膜外输注镇痛用于髋关节置换手术后老年病人的镇痛是安全的,效果确切,不良反应轻。Objective To evaluate the efficaey and safety of continuous epidural analgesia(CEA) with butorphanol in elderly patients undergoing hip replacement.Methods Sixty patients scheduled for selective hip replacement were randomized into group B(n=30) to receive patient-controlled epidural analgesia(PCEA) with butorphanol and group M(n=30) to receive PCEA with morphine.Their pain distribution at 5 time points,postoperative global score and the adverse effects in 48 h were observed.Results The pain distribution at...

关 键 词：布托啡诺 吗啡 术后镇痛 

分 类 号：R614[医药卫生—麻醉学]