黄芪在妊娠期糖尿病患者中的抗氧化活性及临床评价  

Clinical evaluation of the antioxidant activity of astragalus in women with gestational diabetes

作　　者：梁海英[1] 侯峰[1] 丁勇利[1] 张温麑[1] 黄晓晖[1] 张碧云[1] 刘颖[1] 

机构地区：[1]广东省妇幼保健院妇产科,广东广州510010

出　　处：《南方医科大学学报》2009年第7期1402-1404,共3页Journal of Southern Medical University

基　　金：广东省中医药局立项项目(2007187)

摘　　要：目的研究黄芪对妊娠期糖尿病抗氧化活性及其临床疗效的影响。方法选择84例妊娠期糖尿病孕妇,经过规则饮食控制需药物治疗,予胰岛素控制血糖稳定后,随机分为继续胰岛素治疗组(43例)和胰岛素联合黄芪治疗组(41例),测定两组血液超氧化物岐化酶(SOD)的活性、脂质过氧化物(LPO)的水解产物丙二醛(MDA)的含量及血脂、肾功等。结果加用黄芪治疗后,患者血清SOD较对照组明显上升,而MDA较对照组明显下降。黄芪治疗组肾功能及血脂均较对照组下降。结论黄芪可有效控制血糖的升高,减少自由基生成,提高机体抗氧化损伤能力,改善机体功能,在妊娠期糖尿病及其并发症的防治中起一定作用。Objective To evaluate the antioxidant activity of astragalus and its therapeutic effect on gestational diabetes.Methods Eighty-four pregnant women with gestational diabetes were divided into insulin and insulin plus astragalus groups after regular dietary control and insulin treatment to maintain stable blood glucose level.The 43 patients in insulin group received insulin injection,whereas the 41 patients in the other group received treatment with both insulin and astragalus.The SOD activity,MDA level,blood...

关 键 词：黄芪 妊娠 糖尿病 超氧化物岐化酶 脂质过氧化物 

分 类 号：R285[医药卫生—中药学]