短QT综合征的研究进展  

Research Progress of Short QT Syndrome

作　　者：张刚[1] 于晓玲[1] 

机构地区：[1]辽宁医学院附属第一医院,辽宁锦州121000

出　　处：《心血管病学进展》2009年第6期1026-1029,共4页Advances in Cardiovascular Diseases

摘　　要：短QT综合征是近年发现的一种遗传性心脏电生理疾病。目前已有5种与之相关的基因变异被确定:KCNH2(HERG)、KCNQ1、KCNJ2及CACNB2b和CACNA1C。临床表现主要有心房颤动、晕厥反复发作,甚至出现心脏性猝死,但也可无任何症状。Short QT syndrome(SQTs) is a type of hereditary heart electricity physiology disease that was discovered recently.At present,5 types have been determined with related gene variation: KCNH2(HERG),KCNQ1,KCNJ2,CACNB2b,and CACNA1C.Clinically SQTs is associated with atrial fibrillation,syncope,and sudden cardiac death.However,SQTs may not exhibit any symptoms.

关 键 词：短QT综合征 分子遗传学 电生理机制 心脏性猝死 

分 类 号：R541.7[医药卫生—心血管疾病]