Self-assembly behavior of inclusion complex formed by β-cyclodextrin withα-aminopyridine  

作　　者：ZHAO Yanli LIU Yu 

机构地区：[1]Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China

出　　处：《Science China Chemistry》2004年第3期200-205,共6页中国科学（化学英文版）

基　　金：supported by the National Natural Science Foundation of China (Grant Nos. 20272028 and 90306009).

摘　　要：An inclusion complex (1) has been prepared by β-cyclodextrin with α-aminopyridine. The result of X-ray crystallographic analyses showed that the α-aminopyridine molecules in the β-cyclodextrin cavities possess two opposite orientations, i.e. the amine group of α-aminopyridine pointing to the primary side (1a, occupancy: 41.2%) or the secondary side (1b, occupancy: 58.8%) of β-cyclodextrin, forming two scalelike supramolecular aggregations. The studies of 2D NMR and circular dichroism spectra indicated that the α-aminopyridine molecule is deeply embedded in the β-cyclodextrin cavity to form host-guest inclusion complex, showing a circular dichroism spectrum induced by the chiral cavity of cyclodextrin. The results obtained are helpful for understanding the molecular recognition and aggregation mechanism between the host and guest.An inclusion complex (1) has been preparted by cyclodextrin with22.7( )]-aminopyridine. The result of X-[(ray crystallo)(graphic analyses showed that th)]eα-aminopyridine molecules in thecyclodextrin cavities possess two opposite orientations, i.e. the amine group ofα-aminopyridine pointing to the primary side (1a, occupancy:41.2%) of the secondary side (1b, occupancy:58 ofβ-[(cyclodextrin, forming two scaleli)(ke )]supramolecular aggregations. The studies of 2D NMR and circular dichroism spectra indicated that theaminopyridine molecule is deeply embedded in thecyclodextrin cavity to form host-guest inclusion complex, showing a circular dichroism spectrum induced by the chiral cavity of cyclodextrin. The results obtained are helpful for understanding [(the molecular recognition and aggregation mechanism between the host and guest.

关 键 词：aggregation  crystal structure  cyclodextrin  hydrogen bonds  INCLUSION complex. 

分 类 号：N[自然科学总论]