针刺对慢性高眼压兔视网膜、视神经超微结构影响的研究  

The Protective Effect of Acupuncture Treatment on Retinal and Optic Nerve Axonal Ultrastructure in Rabbit Eyes with Chronic Elevated IOP

作　　者：孙河[1] 张慧 

机构地区：[1]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040 [2]大庆医学高等专科学校,黑龙江大庆163312

出　　处：《针灸临床杂志》2010年第5期52-55,共4页Journal of Clinical Acupuncture and Moxibustion

基　　金：黑龙江省自然基金项目;编号:D0342

摘　　要：目的:观察针刺对眼压已控制的慢性高眼压兔的视神经保护作用,并探讨其机制。方法:以大耳白兔为实验动物,通过前房注射复方卡波姆溶液造成慢性高眼压模型,28天后通过滤过性手术使眼压恢复正常。分层随机分为模型组、针刺组、电针组、神经营养剂组,并设正常组。治疗28天后,观察各组兔视网膜、视神经形态学与视神经轴突定量的改变。结果:实验结束时各组动物出现显著差异,与模型组相比,治疗组兔视网膜、视神经超微结构损伤较轻,视神经轴突数及视神经轴突占视神经面积百分比明显高于模型组(P<0.01)。结论:针刺能保护高眼压损害的视神经,作用主要表现为减轻视网膜超微结构损伤,增加视神经轴突的存活率。Objective:To observe the protective effects of acupuncture treatment on optic nerve of the rabbits model whose intraocular pressure was reduced to normal after chronic intraocular pressure(IOP)elevated,and study the mechanism of it.Methods:Elevated intraocular pressure was gotten by injection of 0.3 carbomer into anterior chamber of albino rabbit.IOP was reduced to normal through conventional glaucomatous trabeculetomy after the intraocular pressure elevated continuously for 28 days.It is randomly divided i...

关 键 词：针刺 慢性高眼压 视网膜 视神经轴突 

分 类 号：R245[医药卫生—针灸推拿学]