重视儿童非肿瘤性EB病毒感染疾病的研究  

Emphasis on the Study of Non-Malignant Diseases Associated with Epstein-Barr Virus Infection in Children

作　　者：谢正德[1] 申昆玲[1] 

机构地区：[1]首都医科大学附属北京儿童医院北京市儿科研究所病毒研究室

出　　处：《首都医科大学学报》2010年第2期213-216,共4页Journal of Capital Medical University

基　　金：首都医学发展基金(编号2007-2062)资助项目~~

摘　　要：Epstain-Barr病毒(Epstain-Barr virus,EBV)是一种重要的肿瘤相关病毒,成人感染率超过90%。EB病毒与鼻咽癌、霍奇金和非霍奇金淋巴瘤、胃癌、移植后淋巴增生症等多种肿瘤的发生密切相关。本文介绍了EB病毒感染的实验室诊断方法及其临床应用,重点介绍了儿童常见非肿瘤性EB病毒感染疾病(传染性单核细胞增多症、慢性活动性EB病毒感染、EB病毒相关噬血淋巴组织细胞增生症)的临床特征、诊断指南及需要进一步研究的问题。Epstain-Barr virus(EBV) is an important tumor-related virus,infects over 90% of the world s adult population.EBV is also associated with a wide variety of malignancies including nasopharyngeal carcinoma(NPC),Hodgkin and non-Hodgkin lymphomas,gastric carcinoma,post-transplant lymphoproliferative disorder(PTLD).This review introduced laboratory diagnostic assays of EBV infection,and focused on clinical feature and diagnostic guidline of non-malignant diseases associated with EBV infection in children(includin...

关 键 词：EB病毒 传染性单核细胞增多症 慢性活动性EB病毒感染 EB病毒相关噬血淋巴组织细胞增生症 儿童 

分 类 号：R725.1[医药卫生—儿科]