Two new 19-oxygenated ent-kaurane diterpenoids from Isodon pharicus  

Two new 19-oxygenated ent-kaurane diterpenoids from lsodon pharicus

作　　者：Zhao, Yong Pu, Jian Xin Huang, Sheng Xiong Yang, Li Bin Xiao, Wei Lie Li, Li Mei Ding, Li Sheng Sun, Han Dong 

机构地区：[1]Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China [2]Yunnan Normal Univ, Coll Chem & Engn, Kunming 650092, Peoples R China [3]Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China

出　　处：《Chinese Chemical Letters》2010年第1期81-84,共4页中国化学快报（英文版）

基　　金：supported financially by the NSFC(No.30772637 to H.-D.Sun);the NSFC-joint Foundation of Yunnan Province(No.U0832602 to H.-D.Sun);the Major State Basic Research Development Program of China(No. 2009CB522303 and 2009CB940900);the Natural Science Foundation of Yunnan Province(No.2008CD 162);the Key Project of Knowledge Innovation Project of CAS(No.KSCX2-YW-R-25).

摘　　要：Two new 19-oxygenated ent-kaurane diterpenoids,pharicinins D and E(1 and 2),together with an artifact,pharicinin D acetal (3) were isolated from the leaves of Isodon pharicus.Their structures were determined by 1D and 2D NMR spectroscopic analysis. All of them were evaluated for their cytotoxicity.

关 键 词：Isodon pharicus LABIATAE ent-Kaurane diterpenoid 

分 类 号：R284[医药卫生—中药学]