Endoscopic submucosal dissection in dogs in a World Gastroenterology Organisation training center  

作　　者：Miguel A Tanimoto Gonzalo Torres-Villalobos Rikiya Fujita Patricio Santillan-Doherty Jorge Albores-Saavedra German Gutierrez Luis A Martin-del-Campo Carlos Bravo-Reyna Octavio Villanueva Jose J Villalobos Misael Uribe Miguel A Valdovinos 

机构地区：[1]Department of Gastroenterology and World Gastroenterology Organisation Training Center, National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City 14000, Mexico [2]Department of Surgery and Experimental Surgery, National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City 14000, Mexico [3]The Cancer Institute Hospital of JFCR Tokyo, Tokyo 135-8550, Japan [4]Department of Pathology, National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City 14000, Mexico [5]Department of Experimental Surgery, National Institute of Medical Sciences and Nutrition Salvador Zu- biran, Mexico City 14000, Mexico [6]Animal lab and Department of Experimental Research, National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City 14000, Mexico

出　　处：《World Journal of Gastroenterology》2010年第14期1759-1764,共6页世界胃肠病学杂志（英文版）

摘　　要：AIM: To evaluate if canine models are appropriate for teaching endoscopy fellows the techniques of endoscopic submucosal dissection (ESD). METHODS: ESD was performed in 10 canine models under general anesthesia, on artificial lesions of the esophagus or stomach marked with coagulation points. After ESD, each canine model was euthanized and surgical resection of the esophagus or stomach was carried out according to "The Principles of Humane Experimental Technique, Russel and Burch". The ESD specimens were fixed with needles on cork submerged in a formol solution with the esophagus or stomach, and delivered to the pathology department to be analyzed. RESULTS: ESD was completed without complications using the Hook-knife in five esophageal areas, with a procedural duration of 124 ± 19 min, a length of 27.4 ± 2.6 mm and a width of 21 ± 2.4 mm. ESD was also completed without complications using the IT-knife2 in five gastric areas, with a procedural duration of 92.6 ± 19 min, a length of 32 ± 2.5 mm and a width of 18 ± 3.7 mm. CONCLUSION: ESD is feasible in the normal esopha- gus and stomach of canine models, which are appropriate for teaching this technique.AIM: To evaluate if canine models are appropriate for teaching endoscopy fellows the techniques of endoscopic submucosal dissection (ESD). METHODS: ESD was performed in 10 canine models under general anesthesia, on artificial lesions of the esophagus or stomach marked with coagulation points. After ESD, each canine model was euthanized and surgical resection of the esophagus or stomach was carried out according to 'The Principles of Humane Experimental Technique, Russel and Burch'. The ESD specimens were fi...

关 键 词：Endoscopic mucosal resection Endoscopic submucosal dissection Stomach neoplasms TRAINING 

分 类 号：R656[医药卫生—外科学]