戒烟药物研究进展  

Progress of smoking cessation drugs

作　　者：廖若敏[1] 周新[1] 

机构地区：[1]上海交通大学附属第一人民医院呼吸科,上海200080

出　　处：《世界临床药物》2009年第11期695-697,共3页World Clinical Drug

摘　　要：烟草依赖为一种慢性尼古丁成瘾性疾病。尼古丁强化效应是吸烟者戒烟失败的主要原因。吸烟者成功戒烟往往需戒烟药物的辅助治疗,常用戒烟药物有一线戒烟药物(如尼古丁替代、安非他酮及伐尼克兰)和二线戒烟药物(如可乐定和去甲替林等),以及其他戒烟药物。Tobacco dependence is defined as a chronic disease of nicotine addiction and it is also a recurrent disease. Strengthening effect of nicotine is the primary factor leading to failure of smoking cessation.Those holding off smoking successfully may need adjunctive therapy such as drugs.The first-line smoking cessation medications include nicotine replacement,bupropion and varenicline.The second-line drugs include clonidine and nortriptyline etc.This paper reviews the progress of smoking cessation drugs.

关 键 词：戒烟 烟草依赖 尼古丁成瘾 慢性 

分 类 号：R971[医药卫生—药品]