全复配食用菌提物的抗衰老作用研究  

Anti-aging activities of effective combination of extraction from edible fungi

作　　者：王琪[1] 孙颖[2] 莫非[2] 朱明洁[2] 马智超[2] 文达[1] 段友容[2] 

机构地区：[1]四川大学华西药学院,成都610041 [2]上海交通大学肿瘤研究所肿瘤靶向与新型给药系统实验室,上海200032

出　　处：《世界临床药物》2009年第11期666-669,675,共5页World Clinical Drug

摘　　要：目的探讨全复配食用菌提物的抗衰老作用。方法以果蝇生存试验比较不同浓度全复配食用菌提物对果蝇生存期的影响;以果蝇及小鼠的血清超氧化物歧化酶(SOD)活性和丙二醛(MDA)含量比较不同浓度全复配食用菌提物的抗氧化功能。结果全复配食用菌提物可延长果蝇的生存时间,降低果蝇及小鼠的MDA含量,增强SOD活性。结论全复配食用菌提物具有抗衰老功能,提高机体内源性抗氧化酶活性、降低过氧化水平可能是其作用途径之一。Objective To investigate the anti-aging activities of effective combination of extraction from edible fungi. Methods The life-spans of Drosophila melanogasters which were fed by combination of extraction from edible fungi of different concentration were compared.The activities of superoxide dismutase(SOD) and the contents of erythrocyte malondialdehyde(MDA) were examined in Drosophila melanogasters and mice.Results Certain concentration of effective combination of extraction from edible fungi could prolong ...

关 键 词：全复配食用菌提物 寿命 超氧化物歧化酶 丙二醛 

分 类 号：R285.5[医药卫生—中药学]