含缩氨基脲结构的二苯甲酮腙衍生物的合成与生物活性  

Synthesis and Biological Activity of Benzophenonehydrazone Derivatives Containing Semicarbazone Structure

作　　者：刘永榜[1] 彭伟立[2] 郁林军[2] 邢家华[2] 陈杰[2] 夏旭建[2] 沈德隆[1] 

机构地区：[1]浙江工业大学农药研究所,杭州310014 [2]浙江省化工研究院,杭州310023

出　　处：《农药》2010年第6期407-409,共3页Agrochemicals

摘　　要：以对硝基苯甲酰氯、卤代苯、甲烷磺酰氯、水合肼等为原料合成4-卤代-N-甲基-4'-甲烷磺酰氨基二苯甲酮腙,后者与苯基异氰酸酯反应得到23种含缩氨基脲结构的二苯甲酮腙新型化合物。对所得化合物结构均经1HNMR和MS表征;初步生物活性测试表明这些化合物具有良好的杀虫活性。A series of benzophenonehydrazone were synthesized using 4-nitrobenzoyl chloride,halogenatebenzene, methanesulfonyl chloride,hydrazine hydrate,etc.as starting materials,which was then treated with various phenylisocyanates to give twenty-three novel benzophenonehydrazone derivatives containing semicarbazone structure. The structures of the products were characterized by 1 H NMR and MS;preliminary bioassay indicated that some compounds had excellent insecticidal activities.

关 键 词：苯基异氰酸酯 二苯甲酮腙 缩氨基脲 合成 生物活性 

分 类 号：TQ450.21[化学工程—农药化工]