QTL alleles on chromosome 7 from fatty Meishan pigs reduce fat deposition  

作　　者：岳根华 Petra Beeckmann Gerhard Moser Elisabeth Müller Hans Bartenschlager1 Stanislav Cepica Jaroslav Schrffel Antonin Stratil Hermann Geldermann 

机构地区：[1]Department of Animal Breeding and Biotechnology,University of Hohenheim [2]Institute of Animal Physiology and Genetics,Academy of Sciences of the Czech Republic

出　　处：《Science China(Life Sciences)》2003年第1期10-17,共8页中国科学（生命科学英文版）

摘　　要：For detecting QTL in the whole swine genome,1068 pigs from three F2 populations con-structed by crossing European Wild boar and Pietrain (W譖),Meishan and Pietrain (M譖),and Wild Boar and Meishan (W譓) were genotyped for genetic markers evenly spaced at approximately 20 cM inter-vals. A QTL analysis was performed using a least-squares method. Here the results of the QTL analysis on the porcine chromosome 7 are presented. QTL for carcass composition (e.g.head weight,carcass length,backfat depth,abdominal fat and bacon meat) were mapped in the chromosomal region CYPA/CYPD-TNFB-S0102 in M譖 and W譓,but not in W譖. The QTL was additive. Surprisingly, in contrast to the parental phenotype, the QTL alleles from fatty Meishan were associated with thinner backfat than Pietrain and Wild Boar alleles,suggesting that the genome of the fatty Meishan pig contains genes which can reduce fat content of carcass substantially.For detecting QTL in the whole swine genome,1068 pigs from three F2 populations con-structed by crossing European Wild boar and Pietrain (W譖),Meishan and Pietrain (M譖),and Wild Boar and Meishan (W譓) were genotyped for genetic markers evenly spaced at approximately 20 cM inter-vals. A QTL analysis was performed using a least-squares method. Here the results of the QTL analysis on the porcine chromosome 7 are presented. QTL for carcass composition (e.g.head weight,carcass length,backfat depth,abdominal fat and bacon meat) were mapped in the chromosomal region CYPA/CYPD-TNFB-S0102 in M譖 and W譓,but not in W譖. The QTL was additive. Surprisingly, in contrast to the parental phenotype, the QTL alleles from fatty Meishan were associated with thinner backfat than Pietrain and Wild Boar alleles,suggesting that the genome of the fatty Meishan pig contains genes which can reduce fat content of carcass substantially.

关 键 词：genomics  pig  SSC7  QTL  backfat. 

分 类 号：Q343.1[生物学—遗传学]