老年冠心病患者血清胆红素和血脂测定及临床意义  

Effect of serum total bilirubin and lipids in elderly patients with coronary heart disease

作　　者：周晓钢[1] 王冬梅[2] 周景春[2] 高学文[2] 

机构地区：[1]内蒙古医学院生物化学教研室 [2]内蒙古自治区医院,010059

出　　处：《中国老年保健医学》2003年第2期21-23,共3页Chinese Journal of Geriatric Care

摘　　要：目的本文观察了老年冠心病患者血清胆红素水平与血清脂质的关系。方法对97例老年冠心病患者及48例老年对照组的血清胆红素(TB)及血清甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白 AI(ApoAI)、载脂蛋白 B(ApoB_(100))、脂蛋白(a)[Lp(a)]进行了测定。结果老年冠心病患者血清 TB 含量显著低于同龄对照组;老年冠心病患者血清 TC、LDL-C 水平显著高于对照组;而 HDL-C 水平却极显著低于对照组(P<0.01);血清 TC、ApoA I、ApoB 及 Lp(a)水平两组比较无显著性差异。结论老年人低血清胆红素可能是动脉粥样硬化和冠心病危险因素之一。Objective To explore the variation of concentration of serum total bilirubin (TB)and lipids in coronary heart disease(CHD).Methods 155 elderly patients were ran- domly divided into two groups:CHD group(n=97)and normal group(n=48).The levels of bil- imbin and lipids in serum were measured and compared.Results The concentration of TB in serum in CHD group was significant lower than that in normal group(P<0.05).The serum trig- lyceride(TG),low density lipoprotein cholesterol(LDL-C)levels in the CHD group were obvious higher than in the normal group(P<0.05);high-density lipopretein-cholesterol(HDL-C)is obviously increased in CHD group(P<0.05);There is no difference of cholesterol(TC)and apo- lipoprotein B(ApoB),lipoprotein(a)[Lp(a)],apolipoprotein AI(ApoAI)between two groups(P >0.05).Conclusions The low concentration of TB in serum might be a risk factor for old- aged CHD patients.

关 键 词：胆红素 血脂 冠心病 老年人 

分 类 号：R541.4[医药卫生—心血管疾病]