亚甲基蓝光度法测苯唑西林  

Spectrophotometric determination of oxacillin with methylene blue

作　　者：江虹[1] 庞向东[1] 赖富华[1] 

机构地区：[1]长江师范学院化学化工学院,重庆408100

出　　处：《分析试验室》2010年第11期45-47,共3页Chinese Journal of Analysis Laboratory

基　　金：重庆市教委科技基金(KJ071304);长江师范学院科研项目(2008xky39)资助

摘　　要：在pH8.6～9.8的条件下,亚甲基蓝与苯唑西林反应生成蓝色离子缔合物。体系的最大吸收波长位于606nm,线性范围为0～4.0mg/L,表观摩尔吸光系数为2.60×104L·mol-1.cm-1,探讨了适宜的反应条件、方法的精密度及可靠性。方法已用于药物中阿莫西林的测定。Under pH 8.6～9.8 condition,methylene blue reacts with oxacillin to form a blue ion-association complex.The maximum absorption wavelength was located at 606 nm,and the linear range was 0～4.0 mg/L and the apparent molar absorptivity (ε) was 2.60×104 L·mol-1·cm-1.The optimum reaction conditions and the methodological precision and reliability were studied.This method has been applied to the determination of oxacillin in the oxacillin medicament with satisfactory results.

关 键 词：苯唑西林 亚甲基蓝 分光光度法 

分 类 号：R927[医药卫生—药学]