中国被毛孢发酵物对小鼠T、B淋巴细胞转化功能的影响  

Effects of Hirsutella Sinensis Strain Fermentation on The Proliferation of T and B Lymphocyte in Mouse

作　　者：黄河[1] 姜建民[2] 傅惠英[3] 

机构地区：[1]温州医学院第二附属医院,温州325027 [2]浙江省中药研究所 [3]浙江大学医学院

出　　处：《浙江中医药大学学报》2010年第4期604-605,共2页Journal of Zhejiang Chinese Medical University

摘　　要：[目的]观察中国被毛孢发酵物对正常小鼠T、B淋巴细胞转化功能的影响。[方法]给予小鼠高(1.0g·kg-1)、低(0.1g·kg-1)剂量的中国被毛孢发酵物,观察其对小鼠T、B淋巴细胞转化功能的影响。[结果]中国被毛孢发酵物和冬虫夏草均能显著提高正常小鼠脾T和B淋巴细胞转化刺激指数(P<0.05,P<0.01);[结论]中国被毛孢发酵物和冬虫夏草均均能提高正常小鼠免疫功能。[Objective] To observe the proliferation of T and B Lymphocyte in mouse after treated by Hirsutella sinensis strain fermentation.[Methods] Mice were treated with 1.0g·kg-1,0.1g·kg-1 of Hirsutella sinensis strain fermentation by intragastric administration.The proliferation of T and B Lymphocyte from the spleen of mouse is detected by the MTT assay .[Results] Hirsutella sinensis strain fermentation and Cordyceps Sinensis can distinctly increasse the stimulation index (SI) of T and B lymphocyte transformation.[Conclusion] Hirsutella sinensis strain fermentation and Cordyceps Sinensis are able to enhance immune function of normal mouse.

关 键 词：中国被毛孢发酵物 T淋巴细胞 B淋巴细胞 

分 类 号：R285.5[医药卫生—中药学]