IVF-ET周期中胚胎移植日血清雌激素下降幅度与妊娠的关系  

Relationship between the pregnancy and the level Down-range of Serum Estradiol OnIn-vitro Fertilization Embryo Transfer Cycle

作　　者：罗薇[1] 黄绘[1] 袁燕[1] 

机构地区：[1]贵阳市妇幼保健院,550003

出　　处：《贵州医药》2011年第2期114-117,共4页Guizhou Medical Journal

摘　　要：目的探讨控制性超促排卵(COH)周期中胚胎移植日雌激素下降幅度与体外受精-胚胎移植(IVF-ET)结局的关系。方法回顾性分析284个接受长方案控制性超排卵的IVF-ET(包括ICSI)周期,于注射HCG日和ET日分别测定血清E2值,根据其移植日血清E2水平下降幅度分为6组,A组:66个周期,E2下降幅度<30%;B组:51个周期,E2下降幅度30%~39%;C组:39个周期,E2下降幅度40%~49%;D组:57个周期,E2下降幅度50%~59%;E组:51个周期,E2下降幅度60%~69%;F组:20个周期,E2下降幅度≥70%。结果 ET日血清E2水平呈不同程度的下降,当下降幅度≥50%时胚胎种植率和妊娠率明显降低,差异有显著性(P<0.05)。结论当ET日血清E2水平下降幅度≥50%时会引起胚胎种植率和临床妊娠率的降低。推测在IVF周期中,HCG日至ET日E2值迅速下降幅度可预测其妊娠结局。Objective To investigate the relationship between estrogen level down-range of controlled ovarian hyperstimulation(COH) cycle and in-vitro fertilization-embryo transfer(IVFET) outcomes.Methods In the study 284 IVF-ET cycles were evaluated restrospectively.Serum estadiol was measured on the day of HCG(include ICSI) administration and the day of embryo transfer(ET).According to the down-range of estradiol level on ET day,It was divided into six groups which were group A(<30%,66cycles),group B(30%~39%,51cyc...

关 键 词：雌激素 体外受精-胚胎移植(IVF-ET) 黄体期 妊娠率 

分 类 号：R71[医药卫生—妇产科学]