我院呼吸科2009年11月-2010年2月肺部细菌性感染住院患者抗感染治疗调查分析  

Analysis of Anti-infection Treatment for Inpatients with Pulmonary Infections in Respiratory Department of Our Hospital from Nov. 2009 to Feb. 2010

作　　者：裴保香[1] 金杨红[2] 解立新[1] 罗燕萍[1] 

机构地区：[1]解放军总医院,北京市100853 [2]蚌埠医学院,蚌埠市233010

出　　处：《中国药房》2011年第6期496-498,共3页China Pharmacy

摘　　要：目的:了解我院呼吸科肺部细菌性感染住院患者抗菌药物的应用情况。方法:选取我院呼吸科2009年11月-2010年2月肺部细菌性感染住院患者有效病例165例,分析其抗菌药物的治疗效果、初始经验性用药以及病原学检查,并进行合理性评价。结果:165例患者所应用抗菌药物涉及11类34种,氟喹诺酮类和碳青霉烯类使用频率最高。单用频次排序列前5位的依次为头孢哌酮钠/舒巴坦钠、亚胺培南/西司他丁钠、美罗培南、哌拉西林钠/舒巴坦钠和甲磺酸左氧氟沙星。联合用药占40.66%,以二联用药为主。头孢哌酮钠/舒巴坦钠、亚胺培南/西司他丁钠、哌拉西林钠/舒巴坦钠和甲磺酸左氧氟沙星之间疗效差异无统计学意义,而美罗培南疗效偏低。初始经验性用药现象突出,41.82%符合《社区获得性肺炎诊断和治疗指南》推荐。细菌培养送检率为71.89%,阳性率为39.78%。结论:我院呼吸科肺部感染住院患者应用抗菌药物基本合理,但仍存在不足,有待进一步强化合理用药意识,加强监管力度。OBJECTIVE: To analyze the utilization of antibiotics in the inpatients with pulmonary infection in respiratory department of our hospital. METHODS: 165 inpatients with pulmonary infection from Nov. 2009 to Feb. 2010 were collected and analyzed in respect of therapeutic efficacy, initial empirical drug use and etiology examination, rationality evaluation. RESULTS: 11 categories 34 kinds of antibiotics were adopted in 165 patients, and fluoroquinolones and carbapenem took up the highest proportion. The top 5 ...

关 键 词：抗菌药物 肺部感染 联合用药 疗效 初始经验性用药 

分 类 号：R969.3[医药卫生—药理学]