我院2007-2009年铜绿假单胞菌感染的耐药性分析  

Drug Resistance Analysis of Pseudomonas Aeruginosa Infection in Our Hospital from 2007-2009

作　　者：邓芳[1] 陈开文[1] 张世勇[1] 彭其胜[1] 舒德忠[1] 徐凌[1] 

机构地区：[1]重庆市涪陵区中心医院,重庆市408000

出　　处：《中国药房》2011年第14期1286-1287,共2页China Pharmacy

摘　　要：目的:了解我院铜绿假单胞菌(PAE)的耐药性变迁趋势,为临床合理使用抗菌药物、控制耐药性发展提供参考。方法:回顾性分析我院2007-2009年PAE感染情况,对分离的556株PAE药敏试验结果进行统计、分析。结果:我院分离的PAE对常用的多种抗菌药物均产生了比较严重的耐药性,平均耐药率>50.0%的抗菌药物有头孢曲松(68.31%)、头孢噻肟(66.80%)、庆大霉素(58.19%)、妥布霉素(57.47%)、氨曲南(52.41%)、头孢吡肟(50.29%);敏感率较高的抗菌药物是阿米卡星(80.64%)、头孢他啶(75.34%)、哌拉西林/他唑巴坦(66.37%)、亚胺培南(61.15%)。除头孢曲松耐药率最高且呈逐年增长趋势,氨曲南、头孢吡肟和头孢他啶的耐药率呈递减之外,PAE对其他药物的耐药率基本稳定。结论:PAE的耐药性基本稳定,临床医师在治疗时应根据药敏试验结果有针对性地合理选用抗菌药物,以提高疗效并减少耐药菌株产生。OBJECTIVE:To explore the drug resistance trend of Pseudomonas aeruginosa(PAE) and to provide reference for rational use of antibiotics and drug resistance control.METHODS:PAE infection of our hospital from 2007 to 2009 was analyzed retrospectively.Results of susceptibility test of 556 strains of PAE were analyzed statistically.RESULTS:Isolated PAE produced more serious drug resistance to commonly used antibiotics.The antibiotics with average drug resistance rate>50.0% were ceftriaxone(68.31%),cefotaxime(...

关 键 词：铜绿假单胞菌 抗菌药物 耐药性 

分 类 号：R978.1[医药卫生—药品]