不同光谱的发光二极管阵列光源照射对体外游离胆红素光化学降解效应的影响  

Effect of Various Light-emitting Diode Arrays on the Efficacy of Unconjugated Bilirubin Photochemical Reaction:a Randomized Trial in Vitro

作　　者：胡江[1] 李晓原[1] 赖兴强[2] 刘建中[2] 吴俊超[1] 唐琳[1] 

机构地区：[1]中山大学中山医学院生物医学工程系,广东广州510080 [2]中山大学中山医学院生物学教研室,广东广州510080

出　　处：《中国医学物理学杂志》2011年第1期2444-2446,共3页Chinese Journal of Medical Physics

摘　　要：目的:探讨三种不同光谱范围的发光二极管(LED)阵列光源对体外游离胆红素降解效应的影响。方法:将500μL浓度为205.2μmol/L的胆红素标准液封入5mL的耐热玻璃管制成一个样本管。将所有共54个样本管分为三组,分别经相同光照强度的蓝光、蓝绿混合光和绿光LED阵列照射0h、0.5h、1h、2h、4h和8h,然后通过咖啡因法检测胆红素溶液的吸光度值。结果:与空白对照组比较,蓝光、蓝绿混合光和绿光LED光照均对胆红素有明显的降解作用(P<0.05);其中又以蓝光LED的光化学降解效应最强。结论:光谱是影响新生儿黄疸LED光疗疗效的重要参数,并且蓝光(465±20)nm为LED光疗较适宜光谱范围。Objective:To probe into effect of light-emitting diodes(LED) irradiation with differ light spectrum on the unconjugated bilirubin degradation in vitro.Methods:500 μL bilirubin solution of 205.2 μmol/L was put into 5 mL Pyrex tube to be one sample,and 54 samples were divided into 3 groups,and then irradiated with blue,blue-green and green LEDs of identical irradiance intensity for time intervals:0 h,0.5 h,1 h,2 h,4 h,8 h separately.At last,the absorbency of each sample was determined by modified J-G assay.Re...

关 键 词：新生儿黄疸 发光二极管 光谱 游离胆红素 咖啡因法 

分 类 号：R722.1[医药卫生—儿科]