血清骨钙素在不同年龄段的水平变化及临床意义  

The clinical significance of changes in serum osteocalcin levels in different ages

作　　者：姜利华[1] 张瑾[1] 韩翠华[1] 欧阳巧洪[1] 

机构地区：[1]北京解放军总医院304临床部核医学科,100037

出　　处：《感染．炎症．修复》2005年第3期159-161,共3页Infection Inflammation Repair

摘　　要：目的：探讨不同年龄段血清骨钙素水平的变化。方法：采用放射免疫分析法(RIA)对316例健康人血清骨钙素(BGP)水平进行测定。结果：少年组与青年组、中年组、老年组比较差异非常显著(P＜0．001),青年组与中年组比较差异有显著性(P＜0．05),青年组与老年组比较有明显差异(P＜0．001),中年组与老年组比较有明显差异(P＜0．001)。少年组、中年组男女之间比较无明显差异,青年组男女之间比较差异有显著性(P＜0．05),老年组男、女比较有明显差异(P＜0．001)。结论：血清骨钙素水平随年龄变化而变化。Objective:To study the serum levels of osteocalcin(BGP)in different ages.Methods:Human serum BGP levels in 316 healthy volunteers were measured by radioimmunoassay.Results:There were significant differ- ence in serum BGP levels among teenager group and other groups (P＜0.001),as well as between young group and middle-age group(P＜0.05),teenager group and aged group (P＜0.001),middle-age group and aged group (P＜0.001) respectively.In teenager and middle-age groups no marked difference in serum BGP levels was found between male and female,and in young and aged groups,there was difference with statistical significance between male and female(P＜0.05,or P＜0.01).Conclusion:Human serum BGP levels changed along with ages.

关 键 词：血清骨钙素 放射免疫 成骨细胞 骨代谢 

分 类 号：R81[医药卫生—放射医学]