咪唑-1-乙酸苄酯的合成与表征  

Synthesis and Characterization of Phenylmethyl-2-imidazol-1-ylethanoate

作　　者：于宏伟[1] 孙耀冉[1] 牟微[1] 吕绪佺 徐书排[1] 谭文娟[1] 刘丽丽[1] 

机构地区：[1]石家庄学院化工学院,河北石家庄050035 [2]大庆华科股份有限公司药业分公司,黑龙江大庆163316

出　　处：《化工中间体》2011年第10期58-60,共3页

摘　　要：咪唑-1-乙酸乙酯水解制备出咪唑乙酸2,收率79%,进一步与苯甲醇进行酯化反应,合成出咪唑-1-乙酸苄酯1,收率42%,产品结构经过1HNMR表征。1-Imidazoleacetic acid was synthesized by hydrolytic reaction,the yield was 79%. Phenylmethyl-2-imidazol-1-ylethanoate was prepared by 1-imidazoleacetic acid and benzyl alcohol. The esterification reaction yield was 42%,and product was charactered by 1H NMR.

关 键 词：水解 酯化 咪唑-1-乙酸苄酯 制备 表征 

分 类 号：TQ2[化学工程—有机化工]