空军飞行员角膜内皮细胞的初步分析  

the preliminary analysis of corneal endothelial cell of chinese air force pilot

作　　者：刘兵[1] 茹海霞[1] 马海燕[1] 赵蓉[1] 邵德望[1] 

机构地区：[1]空军总医院眼科,北京100142

出　　处：《中华航空航天医学杂志》2008年第4期249-252,封2,共5页Chinese Journal of Aerospace Medicine

摘　　要：目的 探讨我国空军飞行员角膜内皮细胞密度和形态特征,初步了解细胞密度和形态学的生理学参数.方法 应用角膜内皮细胞显微镜及仪器自带的角膜内皮细胞分析系统,对男性56例(112眼)现役飞行员角膜内皮细胞进行了观察,同时选取30例(60眼)与其年龄和裸眼视力具有可比性的健康男性作为对照组,两组进行分析和比较.结果 数据显示空军飞行员平均角膜内皮细胞密度为2797.0±330.3个/mm2,显著低于对照组的2917.57±318.04个/mm2(t=2.286,p=0.024).平均六角形细胞构成比,飞行员组(56.46±7.19)显著低于对照组(60.33±7.68),差异有显著性意义(t=3.253,p=0.001).飞行员组和对照组随着年龄的增加,六角形细胞构成比均逐渐减少(r=-0.395、-0.268,p=0.000、0.038).通过偏相关系数分析,在年龄因素控制条件下,飞行员飞行时间的延长伴随着细胞平均面积的增大(r=0.244,p=0.01).结论 对飞行员角膜内皮细胞形态学参数的测定和初步数据分析将有助于进一步了解高速飞行情况下眼角膜内皮的变化.objegtive to preliminarily study the endothelial density baseline and the morphological characteristics of the corneal endothelial cell of chinese air force pilot. metheds density and morphology of corneal endothelial cells were observed by topcon-2000 noncontact specular microscope and analyzed by imagenet 2000 software(version 2.53)on 56 pilots(112 eyes)while other 30 healthy men(60 eyes)who were with the comparable age and uncorrected visual acuity were compared and analyzed as the control group. results the data showed that the average corneal endothelial cell density was 2797.0±330.3/mm2 in pilot group which was significantly lowet than 2917.57±318.04/mm2 in control group(t=2.286,p=0.024).the mean constituent ratio of hexagonal cell was 56.46±7.19 in pilot group compared with 60.33±7.68 in control group(t=8.253,p=o.001)and it was gradually reduced with the age growing in both groups(r=-0.395,-0.268,p=0.000.0.038).with the growing of flying hours the mean area of cell was increased under the eontrolled age factor according to partial correlation analysis(r=0.244,p=0.0 1).conclusions measuring of the corneai endothelial cellular morphologic parameters and implementing corresponding analysis are helpful to know pilot's corneal endotheliurn changes in flight.

关 键 词：内皮 角膜 细胞计数 细胞形态学 

分 类 号：R85[医药卫生—航空、航天与航海医学]