Study on hemodynamics in patient-specific thoracic aortic aneurysm  

作　　者：Ai-Ke Qiao,~(1,a)) Wen-Yu Fu,~(2,3) and You-Jun Liu~(1,b)) 1)College of Life Science and Bioengineering,Beijing University of Technology,Beijing 100124,China 2)College of Mechanical and Electrical Engineering,Beijing Union University,Beijing 100124,China 3)College of Mechanical Engineering and Applied Electronics Technology,Beijing University of Technology, Beijing 100101,China 

出　　处：《Theoretical & Applied Mechanics Letters》2011年第1期69-72,共4页力学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(Grant Nos.10972016 and 10872013);Natural Science Foundation of Beijing (Grant Nos.3092004 and 3092005)

摘　　要：The objective of this study is to investigate the hemodynamics in patient-specific thoracic aortic aneurysm and discuss the reason for formation of aortic plaque.A 3-Dimensional pulsatile blood flow in thoracic aorta with a fusiform aneurysm and 3 main branched vessels was studied numerically with the average Reynolds number of 1399 and the Womersley number of 19.2.Based on the clinical 2-Dimensional CT slice data,the patient-specific geometry model was constructed using medical image process software.Unsteady,incompressible,3-Dimensional Navier-Stokes equations were employed to solve the flow field.The temporal distributions of hemodynamic variables during the cardiac cycle such as streamlines,wall shear stresses in the arteries and aneurysm were analyzed. Growth and rupture mechanisms of thoracic aortic aneurysm in the patient can be analyzed based on patient-specific model and hemodynamics simulation.The objective of this study is to investigate the hemodynamics in patient-specific thoracic aortic aneurysm and discuss the reason for formation of aortic plaque.A 3-Dimensional pulsatile blood flow in thoracic aorta with a fusiform aneurysm and 3 main branched vessels was studied numerically with the average Reynolds number of 1399 and the Womersley number of 19.2.Based on the clinical 2-Dimensional CT slice data,the patient-specific geometry model was constructed using medical image process software.Unsteady,incompressible,3-Dimensional Navier-Stokes equations were employed to solve the flow field.The temporal distributions of hemodynamic variables during the cardiac cycle such as streamlines,wall shear stresses in the arteries and aneurysm were analyzed. Growth and rupture mechanisms of thoracic aortic aneurysm in the patient can be analyzed based on patient-specific model and hemodynamics simulation.

关 键 词：thoracic aneurysm CT image CFD model wall shear stress HEMODYNAMICS 

分 类 号：R543.1[医药卫生—心血管疾病]